Searchable abstracts of presentations at key conferences in endocrinology

ea0019s37 | Phosphoinositide 3-kinase (PI3K) signalling in health and disease: an old system with new potential | SFEBES2009

PI3 kinase inhibitory drugs: fantasy or reality?

Workman Paul

The PI3 kinase family plays an important role in controlling many critical biological processes. There is accumulating evidence that PI3 kinase signalling is involving in a range of diseases and that PI3 kinase inhibitors could offer considerable therapeutic potential. This presentation will focus on the discovery and development of PI3 kinase inhibitors for cancer treatment. The availability of potent and selective PI3 kinase inhibitors is particularly timely given the accumu...